yqhH

168

similar to SNF2 helicase

Locus: BSU_24580

Molecular weight: 64.50 kDa

Isoelectric point: 8.38

Protein length: 557 aa

Gene length: 1674 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: yqhH

Genomic Context

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Categories containing this gene/protein

Information processing, Genetics, Genetics/ other/ based on similarity

Information processing, Genetics, Newly identified competence genes

Lifestyles, Sporulation, Sporulation proteins, Sporulation proteins/ other

List of homologs in different organisms, belongs to COG0553 (Galperin et al., 2021)

This gene is a member of the following regulons

SigF regulon

Gene

Coordinates: 2,549,775  2,551,448

Phenotypes of a mutant

poorly transformable PubMed

The protein

Protein family

helicase family (according to UniProt)
SNF2/RAD54 helicase family (with YwqA, according to UniProt)

Domains

Helicase ATP-binding domain (aa 70-224) (according to UniProt)
Helicase C-terminal domain (aa 363-524) (according to UniProt)

Structure

1Z6A (PDB) (from Sulfolobus solfataricus, 27% identity) 15882619 (PDB)
P54509 (AlphaFold)

Expression and Regulation

Operons

Genes: yqhH-yqhG

Description

expressed early during sporulation

Regulation

expressed early during sporulation in the forespore (SigF) PubMed

Sigma factors

SigF: sigma factor, PubMed, in sigF regulon

Biological materials

Mutant

MGNA-C418 (yqhH::erm), available at the NBRP B. subtilis, Japan
BKE24580 (yqhH::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCTTTGAAACCGCCTT,  downstream forward: _UP4_TAGCCTGTAAGGAGGTTTTA
BKK24580 (yqhH::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCTTTGAAACCGCCTT,  downstream forward: _UP4_TAGCCTGTAAGGAGGTTTTA

References

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