yjcD

168

similar to ATP-dependent DNA helicase

Locus: BSU_11820

Molecular weight: 86.79 kDa

Isoelectric point: 8.02

Protein length: 717 aa

Gene length: 2154 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: yjcD

Genomic Context

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Categories containing this gene/protein

Information processing, Genetics, DNA repair/ recombination/ based on similarity

List of homologs in different organisms, belongs to COG0210 (Galperin et al., 2021)

Gene

Coordinates: 1,253,713 → 1,255,866

The protein

Catalyzed reaction/ biological activity

ATP + H₂O --> ADP + H⁺ + phosphate (according to UniProt)

Protein family

helicase family (according to UniProt)

Domains

UvrD-like helicase ATP-binding domain(aa 134-413) (according to UniProt)
UvrD-like helicase C-terminal domain (aa 414-676) (according to UniProt)

Structure

2PJR (PDB) (PcrA product complex, complex with sulphate ion, Geobacillus stearothermophilus, 36% identity, 55% similarity)
1PJR (PDB) (PcrA substrate complex, complex with DNA, Geobacillus stearothermophilus, 36% identity, 55% similarity)
O31626 (AlphaFold)

Paralogous protein(s)

PcrA

Localization

cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

Genes: yjcD

Description: PubMed

Biological materials

Mutant

MGNA-A159 (yjcD::erm), available at the NBRP B. subtilis, Japan
BKE11820 (ΔyjcD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAACGGGCTTTCCGCAAT,  downstream forward: _UP4_TAACAGCCCGGCAGATTACT
BKK11820 (ΔyjcD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAACGGGCTTTCCGCAAT,  downstream forward: _UP4_TAACAGCCCGGCAGATTACT

References

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