Difference between revisions of "Fla-che operon"

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The [[fla-che operon]] encodes major factors required for [[motility and chemotaxis]]
 
The [[fla-che operon]] encodes major factors required for [[motility and chemotaxis]]
  
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* ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|9657996,8157612,15175317}}
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* The operon is expressed from promoters upstream of ''[[flgB]]'', ''[[ylxF]]'', and ''[[sigD]]'':
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** ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|9657996,8157612,15175317}}
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** ''[[ylxF]]-[[fliK]]-[[flgD]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[flhG]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[swrB]]'' {{PubMed|20233303}}
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** ''[[sigD]]-[[swrB]]'' {{PubMed|9335309}}
  
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* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}}
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* '''[[Sigma factor]]:'''
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** ''[[flgB]]'': [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}}
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** ''[[ylxF]]'': [[SigD]] {{PubMed|20233303}}
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** ''[[sigD]]'': [[SigA]] {{PubMed|9335309}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|14651647}}
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** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|14651647}}
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** reduced expression in the absence of [[PnpA]] (due to accumulation of [[SlrA]]) {{PubMed|26857544}}  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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** [[DegU]]-P: transcription repression {{PubMed|24386445}}
 
** [[DegU]]-P: transcription repression {{PubMed|24386445}}
 
** [[DegU]]-P in complex with [[SwrA]]: transcription activation {{PubMed|24386445}}
 
** [[DegU]]-P in complex with [[SwrA]]: transcription activation {{PubMed|24386445}}
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=== Important publications on the expression and regulation of the ''fla-che'' operon ===
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<pubmed> 26170408, 26857544 </pubmed>
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== Back to [[operons]] ==

Latest revision as of 14:43, 8 October 2017

The fla-che operon encodes major factors required for motility and chemotaxis

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
    • reduced expression in the absence of PnpA (due to accumulation of SlrA) PubMed

Important publications on the expression and regulation of the fla-che operon

Back to operons

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