ylxS

168

similar to ribosome maturation protein

Locus: BSU_16590

Molecular weight: 17.48 kDa

Isoelectric point: 4.48

Protein length: 156 aa

Gene length: 471 bp

Function: ribosome maturation

Product: unknown

Essential: no

Synonyms: ylxS, ymxA, rimP

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0779 (Galperin et al., 2021)

Gene

Coordinates: 1,731,776  1,732,246

The protein

Protein family

• RimP family (single member, according to UniProt)

Structure

• 1IB8 (PDB) (from Streptococcus pneumoniae, 41% identity) PubMed
• P32726 (AlphaFold)

Expression and Regulation

Operons

• Genes: ylxS-nusA-rnpM-rplGA-infB-ylxP-rbfA

  Description: PubMed

  Regulation

  • autoregulation NusA PubMed
  • induced by glucose PubMed
  • expression is reduced in motile cells as compared to non-motile cells PubMed

  Regulatory mechanism

  • stringent response: negative regulation, in stringent response
  • NusA: attenuation, NusA stimulates termination PubMed, in nusA regulon

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon
  • SigB: sigma factor, PubMed, in sigB regulon

Biological materials

Mutant

• BKE16590 (ylxS::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTCTTCCTCCTTGTGC,  downstream forward: _UP4_TAATGAATACAAATGTTTTA
• BKK16590 (ylxS::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTCTTCCTCCTTGTGC,  downstream forward: _UP4_TAATGAATACAAATGTTTTA

References

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