yerH

168

lipoprotein involved in cell division

Locus: BSU_06630

Molecular weight: 44.36 kDa

Isoelectric point: 4.88

Protein length: 396 aa

Gene length: 1191 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: yerH

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG4851 (Galperin et al., 2021)

Gene

Coordinates: 723,635  724,825

Phenotypes of a mutant

• inactivation suppresses the essentiality of mbl PubMed
• an ezrA yerH double mutant has a severe growth defect PubMed

The protein

Structure

• 4HN3 (PDB) (from Listeria monocytogenes, 45% identity)
• O34629 (AlphaFold)

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: pcrB-pcrA-ligA-yerH

  Description: PubMed

  Regulation

  • induced by DNA damage (LexA) PubMed

  Regulatory mechanism

  • LexA: repression, PubMed, in lexA regulon

Biological materials

Mutant

• MGNA-B445 (yerH::erm), available at the NBRP B. subtilis, Japan
• BKE06630 (yerH::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTTTTTCAATAGAAAACACT,  downstream forward: _UP4_TGATAGAAAACCCTTGTGCC
• BKK06630 (yerH::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTTTTTCAATAGAAAACACT,  downstream forward: _UP4_TGATAGAAAACCCTTGTGCC

References

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