Difference between revisions of "RecD2"

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(Extended information on the protein)
 
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* '''Description:''' similar to exodeoxyribonuclease V alpha subunit <br/><br/>
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* '''Description:''' 5'-3' DNA helicase replication fork progression <br/><br/>
  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27480 RecD2]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27480 RecD2]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YrrC RecD2]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RecD2 RecD2]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 88 kDa, 5.08   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 88 kDa, 5.08   
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
** [[SsbA]]-[[RecD2]] {{PubMed|21170359}}
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** [[SsbA]]-[[RecD2]] {{PubMed|24443534,21170359}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''

Latest revision as of 17:51, 22 January 2014

  • Description: 5'-3' DNA helicase replication fork progression

Gene name yrrC
Synonyms
Essential no
Product 5'-3' DNA helicase
Function replication fork progression
Gene expression levels in SubtiExpress: RecD2
Interactions involving this protein in SubtInteract: RecD2
MW, pI 88 kDa, 5.08
Gene length, protein length 2394 bp, 798 aa
Immediate neighbours yrrD, yrrB
Sequences Protein DNA DNA_with_flanks
Genetic context
YrrC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YrrC expression.png















Categories containing this gene/protein

DNA replication

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU27480

Phenotypes of a mutant

  • modest increase in spontaneous mutation rate PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Brian W Walsh, Samantha A Bolz, Sarah R Wessel, Jeremy W Schroeder, James L Keck, Lyle A Simmons
RecD2 helicase limits replication fork stress in Bacillus subtilis.
J Bacteriol: 2014, 196(7);1359-68
[PubMed:24443534] [WorldCat.org] [DOI] (I p)

Audrey Costes, François Lecointe, Stephen McGovern, Sophie Quevillon-Cheruel, Patrice Polard
The C-terminal domain of the bacterial SSB protein acts as a DNA maintenance hub at active chromosome replication forks.
PLoS Genet: 2010, 6(12);e1001238
[PubMed:21170359] [WorldCat.org] [DOI] (I e)