smiA

168

swarming motility inhibitor A, adaptor protein for LonA-mediated degradation of SwrA

Locus: BSU_35319

Molecular weight: 15.00 kDa

Isoelectric point: 4

Protein length: 125 aa

Gene length: 378 bp

Function: control of swarming motility

Product: adaptor protein for LonA-mediated degradation of SwrA

Essential: no

Synonyms: smiA, yvzG

Genomic Context

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List of homologs in different organisms

Gene

Coordinates: 3,631,763  3,632,140

Phenotypes of a mutant

• presence of predifferentiated swarmer cells in liquid medium PubMed
• A mutation in smiA suppresses the motility defect of a ''lytC'' mutant PubMed

The protein

Structure

• C0H3R9 (AlphaFold)

Expression and Regulation

Operons

• Genes: yvyC-fliD-fliS-fliT-smiA-S1350-hpf

  Description: PubMed

  Sigma factors

  • SigD: sigma factor, PubMed, in sigD regulon

Biological materials

Mutant

• available in the Daniel Kearns lab
• BKE35319 (smiA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGGCACTCACCTATTTAC,  downstream forward: _UP4_TAGGCGTGTGTGAGGTATTT
• BKK35319 (smiA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGGCACTCACCTATTTAC,  downstream forward: _UP4_TAGGCGTGTGTGAGGTATTT

Labs working on this gene/protein

• Daniel Kearns, Indiana University, Bloomington, USA, homepage

References

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