Difference between revisions of "MhqA"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU12870&redirect=T BSU12870]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/mhqA.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/mhqA.html]
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:''' extradiol ring-cleavage dioxygenase family (according to Swiss-Prot)
+
* '''Protein family:''' extradiol ring-cleavage dioxygenase family (according to UniProt)
  
 
* '''Paralogous protein(s):''' [[MhqE]], [[MhqO]]
 
* '''Paralogous protein(s):''' [[MhqE]], [[MhqO]]
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU12870&redirect=T BSU12870]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=3OAJ 3OAJ] ([[MhqO]], 34% identical residues)
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=3OAJ 3OAJ] ([[MhqO]], 34% identical residues)
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* '''Additional information:'''
 
* '''Additional information:'''
 +
** number of protein molecules per cell (minimal medium with glucose and ammonium): 183 {{PubMed|24696501}}
  
 
=Biological materials =
 
=Biological materials =

Latest revision as of 08:58, 25 June 2019

  • Description: hydroquinone-specific dioxygenase, confers resistence to methyl-hydroxyquinone

Gene name mhqA
Synonyms ykcA
Essential no
Product hydroquinone-specific dioxygenase
Function resistence to methyl-hydroxyquinone
Gene expression levels in SubtiExpress: mhqA
MW, pI 35 kDa, 5.404
Gene length, protein length 948 bp, 316 aa
Immediate neighbours steT, ykcB
Sequences Protein DNA DNA_with_flanks
Genetic context
YkcA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MhqA expression.png
























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

MhqR regulon

The gene

Basic information

  • Locus tag: BSU12870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: extradiol ring-cleavage dioxygenase family (according to UniProt)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3OAJ (MhqO, 34% identical residues)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by catechol and 2-methylhydroquinone (MhqR) PubMed
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 183 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References