ebrA

168

multidrug efflux transporter

Locus: BSU_17300

Molecular weight: 11.21 kDa

Isoelectric point: 9.37

Protein length: 105 aa

Gene length: 318 bp

Function: multidrug resistance

Product: multidrug efflux transporter

Essential: no

Synonyms: ebrA

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG2076 (Galperin et al., 2021)

Gene

Coordinates: 1,865,058  1,865,375

The protein

Protein family

• paired small multidrug resistance  protein family (PSMR family) PubMed
• drug/metabolite transporter (DMT) superfamily (according to UniProt)
• Small multidrug resistance (SMR) (TC 2.A.7.1) family (according to UniProt)

Structure

• 6D0S (PDB) (human protein, 23% identity)

Paralogous protein(s)

• EbrB

Localization

• cell membrane PubMed

Expression and Regulation

Operons

• Genes: ebrA-ebrB

  Description: PubMed

Biological materials

Mutant

• BKE17300 (ebrA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCATGAATTCTCCTCACT,  downstream forward: _UP4_AATTGGCCGTAAAGGAGTGA
• BKK17300 (ebrA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCATGAATTCTCCTCACT,  downstream forward: _UP4_AATTGGCCGTAAAGGAGTGA

References

Reviews

Loading

Original Publications

Loading