yhaZ

168

similar to alkyl purine DNA glycosylase, probably involved in DNA damage repair

Locus: BSU_09810

Molecular weight: 41.65 kDa

Isoelectric point: 9.08

Protein length: 357 aa

Gene length: 1074 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: yhaZ, alkC

Genomic Context

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Categories containing this gene/protein

Information processing, Genetics, DNA repair/ recombination/ based on similarity

List of homologs in different organisms, belongs to COG4335 (Galperin et al., 2021)

This gene is a member of the following regulons

LexA regulon

Gene

Coordinates: 1,055,143  1,056,216

The protein

Catalyzed reaction/ biological activity

binds to 8-oxoG, abasic, and RNA base DNA lesions PubMed

Structure

5VHV (PDB) (from Pseudomonas flourescens, 41% identity) PubMed
O07541 (AlphaFold)

Expression and Regulation

Operons

Genes: yhaZ

Description: PubMed

Regulation

induced by DNA damage (LexA) PubMed

Regulatory mechanism

LexA: repression, PubMed, in lexA regulon

Additional information

A ncRNA is predicted between 'yhaZ' and 'yhaX' PubMed

Biological materials

Mutant

MGNA-A677 (yhaZ::erm), available at the NBRP B. subtilis, Japan
BKE09810 (yhaZ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATAAACACCGCTTTTTC,  downstream forward: _UP4_TGAGTGAATAAAAAATCCCT
BKK09810 (yhaZ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATAAACACCGCTTTTTC,  downstream forward: _UP4_TGAGTGAATAAAAAATCCCT

References

Reviews

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Original Publications

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