ynzC

168

unknown

Locus: BSU_17880

Molecular weight: 8.67 kDa

Isoelectric point: 10.28

Protein length: 77 aa

Gene length: 234 bp

Function: unknown

Product: unknown

Essential: no

E.C.: null

Synonyms: ynzC

Genomic Context

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List of homologs in different organisms, belongs to COG4224 (Galperin et al., 2021)

Gene

Coordinates: 1,919,459  1,919,692

Phenotypes of a mutant

• increased sensitivity to DNA-damaging agents PubMed

The protein

Protein family

• UPF0291 family (single member, according to UniProt)

Structure

• 2HEP (PDB) (NMR),  3BHP (PDB)
• O31818 (AlphaFold)

Localization

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: yneA-yneB-ynzC

  Description: PubMed

  Regulation

  • induced by DNA damage (LexA) PubMed

  Regulatory mechanism

  • LexA: repression, PubMed, in lexA regulon

  Additional information

  • YneA is rapidly degraded by extracellular proteases (CtpA) PubMed

Biological materials

Mutant

• BKE17880 (ynzC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTAAACTCCTTTATTG,  downstream forward: _UP4_TAATATAAGAGGAATACGGC
• BKK17880 (ynzC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTAAACTCCTTTATTG,  downstream forward: _UP4_TAATATAAGAGGAATACGGC

References

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