comGG

168

DNA transport machinery, minor pseudopilin

Locus: BSU_24670

Molecular weight: 14.40 kDa

Isoelectric point: 9.19

Protein length: 124 aa

Gene length: 375 bp

Function: genetic competence, DNA uptake

Product: minor pseudopilin

Essential: no

Synonyms: comGG

Genomic Context

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Categories containing this gene/protein

Information processing, Genetics, Genetic competence

Lifestyles, Exponential and early post-exponential lifestyles, Genetic competence

Groups of genes, Membrane proteins

List of homologs in different organisms

This gene is a member of the following regulons

SigA regulon, ComK regulon, SigF regulon

Gene

Coordinates: 2,556,137  2,556,511

Phenotypes of a mutant

loss of genetic competence PubMed

The protein

Structure

P25959 (AlphaFold)

Localization

cell surface PubMed

Expression and Regulation

Operons

Genes: comGA-comGB-comGC-comGD-comGE-comGF-comGG-spoIIIL

Description: PubMed

Regulation

expressed early during sporulation in the forespore (SigF) PubMed

Regulatory mechanism

ComK: activation, PubMed, in comK regulon

Sigma factors

SigA: sigma factor, PubMed, in sigA regulon
SigF: sigma factor, PubMed, in sigF regulon

Additional information

the ''comGA-comGB-comGC-comGD-comGE-comGF-comGG-spoIIIL'' operon requires NusA for expression Reference

Biological materials

Mutant

BKE24670 (comGG::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AATAAACCCTCTTGTACGAT,  downstream forward: _UP4_TAAAACAGTGTAAAGGGTAT
BKK24670 (comGG::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AATAAACCCTCTTGTACGAT,  downstream forward: _UP4_TAAAACAGTGTAAAGGGTAT
BP914 ((comGA-comGB-comGC-comGD-comGE-comGF-comGG)::phleo), available in Fabian Commichau's lab

References

Reviews

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Original Publications

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