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− | Biofilms are the result of the multicellular lifestyle of ''B. subtilis''. They are characterized by the formation of a matrix polysaccharide and an amyloid-like protein, [[TasA]].
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− | {| align="right" border="1" cellpadding="2"
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− | |-
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− | |style="background:#ABCDEF;" align="center"|'''Parent categories'''
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− | |''sinR''
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− | |-
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− | |style="background:#ABCDEF;" align="center"| '''Neighboring categories''' || ''sin, flaD ''
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− | |-
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− | |style="background:#ABCDEF;" align="center"| '''Related categories''' || no
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− | |}
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− | __TOC__
| + | [[File:Example.jpg]] |
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− | ==[http://subtiwiki.uni-goettingen.de/pathways/biofilm.html Biofilm formation in ''Subti''Pathways]==
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− | ==Labs working on biofilm formation==
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− | * [[Daniel Kearns]]
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− | * [[Oscar Kuipers]]
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− | * [[Beth Lazazzera]]
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− | * [[Richard Losick]]
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− | * [[Nicola Stanley-Wall]]
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− | ==Key genes and operons involved in biofilm formation==
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− | * matrix polysaccharide synthesis:
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− | ** ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]''
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− | * amyloid protein synthesis
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− | ** ''[[yqxM]]-[[sipW]]-[[tasA]]''
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− | * regulation
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− | ** [[SlrR]]
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− | ** [[SlrA]]
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− | ** [[SinR]]
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− | ** [[SinI]]
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− | ** [[PtkA]]
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− | ** [[TkmA]]
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− | ** [[PtpZ]]
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− | ** [[DegU]]
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− | ** [[RacX]]
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− | * biofilm disassembly
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− | ** [[YlmE]]
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− | * other proteins required for biofilm formation
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− | ** [[SpeA]]
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− | ** [[YmcA]]
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− | ** [[YxaB]]
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− | ==Key reviews==
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− | <pubmed>19054118 19054118 16787201 9891794 20890834 </pubmed>
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− | * additional reviews: {{PubMed|20735481}}
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