hutM

hutM
168

histidine permease

Locus
BSU_39390
Molecular weight
51.41 kDa
Isoelectric point
9.01
Protein length
Gene length
Function
histidine uptake
Product
histidine permease
Essential
no
Synonyms
hutM

Genomic Context

List of homologs in different organisms, belongs to COG0833 (Galperin et al., 2021)

This gene is a member of the following regulons

SigA regulon, CcpA regulon, HutP regulon, CodY regulon

Gene
Coordinates
4,047,538  4,048,965
The protein
Protein family
Structure
7CMH (PDB) (human protein, corresponds to aa 23 ... 356, 25% identity) PubMed
Paralogous protein(s)
cell membrane (according to UniProt)
Expression and Regulation
Operons
Description
Regulation
induced by histidine (HutP) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
CodY: repression, PubMed, in codY regulon
HutP: antitermination, at a protein-dependent RNA switch located between hutP and hutH PubMed, in hutP regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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hutPhutM

2025-05-09 17:34:30

ghost

156

cf3eb91928f3fe61cbc0cd204535c4f9c144314a

0AE45FCE38B0E774CFFC5F6A0A98EEDF6B02F4D4

Biological materials
Mutant
GP3609 (phleo), available in Jörg Stülke's lab
MGNA-B783 (hutM::erm), available at the NBRP B. subtilis, Japan
BKE39390 (hutM::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CACTGTCTCGCCCTCCTTTT,  downstream forward: _UP4_TAATTAAAAAAGCACACCCC
BKK39390 (hutM::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CACTGTCTCGCCCTCCTTTT,  downstream forward: _UP4_TAATTAAAAAAGCACACCCC
References
Reviews
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Original Publications
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Page visits: 4030

Time of last update: 2025-05-17 19:08:18

Author of last update: Jstuelk