rpsB

168

ribosomal protein uS2

Locus: BSU_16490

Molecular weight: 27.00 kDa

Isoelectric point: 6

Protein length: 246 aa

Gene length: 741 bp

Function: translation

Product: ribosomal protein uS2

Essential: yes

Synonyms: rpsB

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0052 (Galperin et al., 2021)

Gene

Coordinates: 1,717,933 1,718,673

Phenotypes of a mutant

• essential PubMed

The protein

Protein family

• universal ribosomal protein uS2 family (single member, according to UniProt)

Structure

• 3J9W (PDB) (the ribosome) PubMed
• P21464 (AlphaFold)

Localization

• ribosome, at the dimer interface of hibernating ribosomes to prevent loss of the protein PubMed

Additional information

• belongs to the 100 most abundant proteins PubMed

Expression and Regulation

Operons

• Genes: rpsB

  Description: PubMed

  Regulation

  • Rel dependent downregulation (Class I) during stringent response PubMed

  Regulatory mechanism

  • stringent response: negative regulation, PubMed, in stringent response
  • RpsB: autorepression, PubMed, in rpsB regulon

• Genes: rpsB-tsf-pyrH-frr

  Description: PubMed

  Regulation

  • Rel dependent downregulation (Class I) during stringent response PubMed

  Regulatory mechanism

  • stringent response: negative regulation, PubMed, in stringent response

Biological materials

LacZ fusion

• pGP602 (in pAC6), available in Stlke lab

References

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