yfmM

168

translation factor, housekeeping subfamily F ABC ATPase

locus: BSU_07420

Molecular weight: 59.02 kDa

pI: 5.11

Protein length: 518 aa

Gene length: 1557 bp

function: unknown

product: housekeeping subfamily F ABC ATPase

essential: no

synonyms: yfmM

List of homologs in different organisms, belongs to COG0488 (Galperin et al., 2021)

Gene

Coordinates: 814,384  815,940

The protein

Protein family

• [wiki|ABC transporter superfamily] (according to UniProt)
• [wiki|ABCF ATPase subfamily] [pubmed|30597160]

[wiki|Domains]

• 2 [wiki|ABC transporter domain]s (aa 4-260, aa 324-518) (according to UniProt)

Structure

• [PDB|3J5S] (EttA from E. coli, 31% identity) [pubmed|24389465]
• [PDB|4FIN] (EttA from E. coli, 31% identity) [pubmed|24389466]
• [AF|O34512]

Paralogous protein(s)

• [protein|F69F15198ACF8A8347C450EEC09F000EECEDEC41|yfmR], [protein|1F56D3275386BB54A774BFA045C09E36D1268471|ydiF], [protein|2F79DB15D359A127C2D833CC0465E18E1725F539|ykpA]

Expression and Regulation

Operons

• genes: [gene|47B644F334A0BD501E77A198A61CE0F22BAB3E5E|yfmM]

  description: [pubmed|22383849]

Biological materials

Mutant

• MGNA-C238 (yfmM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2236 NBRP B. subtilis, Japan]
• BKE07420 ([gene|47B644F334A0BD501E77A198A61CE0F22BAB3E5E|yfmM]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE07420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTTTACACCTCTATCGT,  downstream forward: _UP4_TAATTTATAAAAAAACCCGC
• BKK07420 ([gene|47B644F334A0BD501E77A198A61CE0F22BAB3E5E|yfmM]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK07420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTTTACACCTCTATCGT,  downstream forward: _UP4_TAATTTATAAAAAAACCCGC

References

Reviews

• 24500425,30746819,39716376

Original Publications

• 10092453,24389466,24389465,27006457