lhaT
168
lipoprotein heptaprenylglyceryl N-acetyl transferase, required for the N-acetylation of lipoproteins
locus
BSU_22530
Molecular weight
21.00 kDa
pI
5.354
function
N-acetylation of lipoproteins
product
lipoprotein heptaprenylglyceryl N-acetyl transferase
essential
no
synonyms
ypjA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4347 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,362,407 → 2,362,964
Phenotypes of a mutant
lack of lipoprotein N-acetylation [pubmed|40626731]
The protein
Catalyzed reaction/ biological activity
[metabolite|Ac-HepG] + α-amino cysteine group of diacylglyceryl lipoproteins --> acetylated lipoproteins (the reaction takes place at the outer side of the membrane) [pubmed|40626731]
Structure
[AF|P54392]
[wiki|Localization]
integral membrane protein [pubmed|40626731]
Biological materials
Mutant
MGNA-A424 (ypjA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/424 NBRP B. subtilis, Japan]
BKE22530 (Δ[gene|D2588A01D46535293CFA7FF1A66E9C132FF5F69E|lhaT]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGGCCGCTGCCCTAATA, downstream forward: _UP4_TAAAGACAATGTTGGTCTAT
BKK22530 (Δ[gene|D2588A01D46535293CFA7FF1A66E9C132FF5F69E|lhaT]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGGCCGCTGCCCTAATA, downstream forward: _UP4_TAAAGACAATGTTGGTCTAT
References
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Time of last update: 2025-07-18 19:16:16
Author of last update: Jstuelk