Difference between revisions of "FadG"

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|style="background:#ABCDEF;" align="center"|'''Function''' || fatty acid degradation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || fatty acid degradation
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 84 kDa, 5.889 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14071 fadG]
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2280 bp, 760 aa
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=fadG fadG]'''
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fadH]]'', ''[[ykuH]]''
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 64 kDa, 8.556 
 
|-
 
|-
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAX52614&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1728 bp, 576 aa
 +
|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fadH]]'', ''[[ykzU]]''
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|-
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14071 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14071 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14071 DNA_with_flanks]
 
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|-
 
|-
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ykuG_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ykuG_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|-
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fadG_1479137_1480867_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:fadG_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14071]]
 
|-
 
|-
 
|}
 
|}
  
 
__TOC__
 
__TOC__
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<br/><br/><br/><br/>
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<br/><br/><br/><br/>
  
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<br/><br/><br/><br/><br/><br/><br/><br/>
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= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[utilization of lipids]]}}
 +
 
 +
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[FadR regulon]]}}
  
 
=The gene=
 
=The gene=
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU14071&redirect=T BSU14071]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ykuFG.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ykuFG.html]
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=== Additional information===
 
=== Additional information===
 +
 +
  
  
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
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* '''Interactions:'''
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* '''[[SubtInteract|Interactions]]:'''  
  
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* '''Localization:'''
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* '''[[Localization]]:'''
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU14071&redirect=T BSU14071]
  
 
* '''Structure:'''
 
* '''Structure:'''
  
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34320 O34320]
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* '''UniProt:''' [http://www.uniprot.org/uniprot/C0H407 C0H407]
  
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU14070]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU14070]
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=Expression and regulation=
 
=Expression and regulation=
  
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* '''Operon:'''  
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* '''Operon:''' ''[[fadH]]-[[fadG]]'' {{PubMed|17189250}}
 +
 
 +
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fadG_1479137_1480867_1 fadG] {{PubMed|22383849}}
  
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* '''[[Sigma factor]]:'''  
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* '''Sigma factor:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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** repressed in the absence of long-chain fatty acids ([[FadR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/17189250 PubMed]
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** induced in the presence of long-chain fatty acids ([[FadR]]) {{PubMed|17189250}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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** [[FadR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/17189250 PubMed]
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** [[FadR]]: transcription repression {{PubMed|17189250}}
  
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* '''Additional information:'''  
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* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =

Latest revision as of 13:34, 2 April 2014

  • Description: fatty acid degradation

Gene name fadG
Synonyms ykuG
Essential no
Product unknown
Function fatty acid degradation
Gene expression levels in SubtiExpress: fadG
Metabolic function and regulation of this protein in SubtiPathways:
fadG
MW, pI 64 kDa, 8.556
Gene length, protein length 1728 bp, 576 aa
Immediate neighbours fadH, ykzU
Sequences Protein DNA DNA_with_flanks
Genetic context
YkuG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FadG expression.png






























Categories containing this gene/protein

utilization of lipids

This gene is a member of the following regulons

FadR regulon

The gene

Basic information

  • Locus tag: BSU14071

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: fadG family (according to Swiss-Prot)
  • Paralogous protein(s): YbfG

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • induced in the presence of long-chain fatty acids (FadR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250] [WorldCat.org] [DOI] (P p)

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