secE

168

preprotein translocase subunit

Locus: BSU_01000

Molecular weight: 6.79 kDa

Isoelectric point: 10.47

Protein length: 59 aa

Gene length: 180 bp

Function: protein secretion

Product: preprotein translocase subunit

Essential: yes

Synonyms: secE

Genomic Context

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List of homologs in different organisms, belongs to COG0690 (Galperin et al., 2021)

Gene

Coordinates: 117,532  117,711

Phenotypes of a mutant

• essential PubMed PubMed

The protein

Protein family

• SecE/SEC61-gamma family (single member, according to UniProt)

Domains

• transmembrane protein with a single TM domain

Structure

• 3DL8 (PDB) (structure of the (SecY-SecE-SecG)-SecA complex) PubMed
• Q06799 (AlphaFold)

Localization

• cell membrane (according to UniProt)

Additional information

• B. subtilis secE complements the secretion phenotype of a cold sensitive E. coli secE mutant.

Expression and Regulation

Operons

• Genes: sigH-rpmGB-secE

  Description: PubMed

  Regulation

  • repressed during logrithmic growth (AbrB) PubMed

  Regulatory mechanism

  • AbrB: repression, PubMed, in abrB regulon

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon

References

Reviews

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Original Publications

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