secE

168

preprotein translocase subunit

Locus: BSU_01000

Molecular weight: 6.79 kDa

Isoelectric point: 10.47

Protein length: 59 aa

Gene length: 180 bp

Function: protein secretion

Product: preprotein translocase subunit

Essential: yes

Synonyms: secE

Genomic Context

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Categories containing this gene/protein

Information processing, Protein synthesis, modification and degradation, Protein secretion

Groups of genes, Essential genes

Groups of genes, Membrane proteins

List of homologs in different organisms, belongs to COG0690 (Galperin et al., 2021)

This gene is a member of the following regulons

SigA regulon, AbrB regulon

Gene

Coordinates: 117,532  117,711

Phenotypes of a mutant

essential PubMed PubMed

The protein

Protein family

SecE/SEC61-gamma family (single member, according to UniProt)

Domains

transmembrane protein with a single TM domain

Structure

3DL8 (PDB) (structure of the (SecY-SecE-SecG)-SecA complex) PubMed
Q06799 (AlphaFold)

Localization

cell membrane (according to UniProt)

Additional information

B. subtilis secE complements the secretion phenotype of a cold sensitive E. coli secE mutant.

Expression and Regulation

Operons

Genes: sigH-rpmGB-secE

Description: PubMed

Regulation

repressed during logrithmic growth (AbrB) PubMed

Regulatory mechanism

AbrB: repression, PubMed, in abrB regulon

Sigma factors

SigA: sigma factor, PubMed, in sigA regulon

References

Reviews

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Original Publications

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