ywcH

168

similar to monooxygenase

Locus: BSU_38100

Molecular weight: 36.40 kDa

Isoelectric point: 5.94

Protein length: 333 aa

Gene length: 1002 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: ywcH, ipa-44d

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG2141 (Galperin et al., 2021)

Gene

Coordinates: 3,910,302  3,911,303

The protein

Structure

• 4US5 (PDB) (from Streptomyces bottropensis, 39% identity) PubMed
• P39606 (AlphaFold)

Paralogous protein(s)

• YvbT, CmoO, YceB

Expression and Regulation

Operons

• Genes: nfrA-ywcH

  Description: PubMed

  Regulation

  • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • induced by cell wall stress (Spx) PubMed

  Regulatory mechanism

  • Spo0A: repression, PubMed, in spo0A regulon
  • Spx: activation, PubMed, in spx regulon

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon
  • SigD: sigma factor, PubMed, in sigD regulon

Biological materials

Mutant

• MGNA-B233 (ywcH::erm), available at the NBRP B. subtilis, Japan
• BKE38100 (ywcH::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCCTACCACCTCATCCT,  downstream forward: _UP4_TGATCTTTAAAAAGCCCTGC
• BKK38100 (ywcH::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCCTACCACCTCATCCT,  downstream forward: _UP4_TGATCTTTAAAAAGCCCTGC

References

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