ymaD

168

putative peroxiredoxin

Locus: BSU_17280

Molecular weight: 16.13 kDa

Isoelectric point: 5.2

Protein length: 150 aa

Gene length: 453 bp

Function: protection against oxidative stress

Product: putative peroxiredoxin

Essential: no

Synonyms: ymaD

Genomic Context

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List of homologs in different organisms, belongs to COG1764 (Galperin et al., 2021)

Gene

Coordinates: 1,864,225  1,864,677

Phenotypes of a mutant

• strongly increased the sensitivity of the cells to H₂O₂ PubMed

The protein

Protein family

• osmC/ohr family (with OhrB and OhrA, according to UniProt)

Structure

• 3I07 (PDB) (from Vibrio cholerae, 25% identity)
• O31790 (AlphaFold)

Expression and Regulation

Operons

• Genes: ymaD

  Description: PubMed

• Genes: pghC-ymaD

  Description: PubMed

Biological materials

Mutant

• GP3166 ymaD::mls trpC2 available in Jörg Stülke's lab
• MGNA-B069 (ymaD::erm), available at the NBRP B. subtilis, Japan
• BKE17280 (ymaD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGTTTTGCCTCCTTTTT,  downstream forward: _UP4_GGTGGAGAATAAAGAAAACA
• BKK17280 (ymaD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGTTTTGCCTCCTTTTT,  downstream forward: _UP4_GGTGGAGAATAAAGAAAACA

References

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