LiaI

• Description: maybe involved in resistance to bacitracin
  
  

Gene name	liaI
Synonyms	yvqI
Essential	no
Product	unknown
Function	unknown
MW, pI	13 kDa, 9.303
Gene length, protein length	378 bp, 126 aa
Immediate neighbours	liaH, yvqJ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU33130

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: O32202

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: liaI-liaH-liaG-liaF-liaS-liaR

• Sigma factor: SigA

• Regulation: repressed by glucose (4.3-fold) PubMed, induced by bacitracin (LiaR)
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism: LiaR: transcription activation
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Thorsten Mascher, Karlsruhe Institute of Technology, Germany link