Difference between revisions of "Noc"
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| − | * '''Description:''' | + | * '''Description:''' DNA-binding protein, spatial regulator of cell division to protect the nucleoid, and timing device with an important role in the coordination of chromosome segregation and cell division<br/><br/> |
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' binds specific sites on the chromosome [http://www.ncbi.nlm.nih.gov/sites/entrez/19494834 PubMed] |
| − | * '''Protein family:''' | + | * '''Protein family:''' ParB family (according to Swiss-Prot) |
* '''Paralogous protein(s):''' [[Spo0J]] | * '''Paralogous protein(s):''' [[Spo0J]] | ||
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* '''lacZ fusion:''' | * '''lacZ fusion:''' | ||
| − | * '''GFP fusion:''' | + | * '''GFP fusion:''' available in the [[Jeff Errington]] lab |
* '''two-hybrid system:''' | * '''two-hybrid system:''' | ||
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=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
| + | |||
| + | Jeff Errington, Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/jeff.errington Homepage] | ||
=Your additional remarks= | =Your additional remarks= | ||
Revision as of 18:25, 7 June 2009
- Description: DNA-binding protein, spatial regulator of cell division to protect the nucleoid, and timing device with an important role in the coordination of chromosome segregation and cell division
| Gene name | noc |
| Synonyms | yyaA |
| Essential | no |
| Product | effector of nucleoid occlusion |
| Function | control of cell division |
| MW, pI | 32 kDa, 5.812 |
| Gene length, protein length | 849 bp, 283 aa |
| Immediate neighbours | yyaB, gidB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU40990
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds specific sites on the chromosome PubMed
- Protein family: ParB family (according to Swiss-Prot)
- Paralogous protein(s): Spo0J
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P37524
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion: available in the Jeff Errington lab
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Jeff Errington, Newcastle, UK Homepage
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
