Difference between revisions of "TreA"
| Line 35: | Line 35: | ||
=== Basic information === | === Basic information === | ||
| − | * '''Locus tag:''' | + | * '''Locus tag:''' BSU07810 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| Line 80: | Line 80: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39795 P39795] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39795 P39795] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU07810] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/3.2.1.93 3.2.1.93] 3 | * '''E.C. number:''' [http://www.expasy.org/enzyme/3.2.1.93 3.2.1.93] 3 | ||
Revision as of 14:21, 3 June 2009
- Description: phospho-alpha-glucosidase
| Gene name | treA |
| Synonyms | treC |
| Essential | no |
| Product | phospho-alpha-glucosidase |
| Function | trehalose utilization |
| MW, pI | 65 kDa, 4.895 |
| Gene length, protein length | 1683 bp, 561 aa |
| Immediate neighbours | treP, treR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU07810
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate (according to Swiss-Prot)
- Protein family: glycosyl hydrolase 13 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P39795
- KEGG entry: [3]
- E.C. number: 3.2.1.93 3
Additional information
Expression and regulation
- Regulation: repressed by glucose (CcpA)
- Regulatory mechanism: CcpA: transcription repression
- Additional information:
Biological materials
- Mutant: GP1118 (spc), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Helfert C, Gotsche S, Dahl MK. (1995) Cleavage of trehalose-phosphate in Bacillus subtilis is catalysed by a phospho-alpha-(1-1)-glucosidase encoded by the treA gene. Mol Microbiol. Apr;16(1): 111-120. PubMed
