Difference between revisions of "Ogt"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU13540
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P11742 P11742]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P11742 P11742]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU13540 BSU13540]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU13540]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.1.1.63 2.1.1.63]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.1.1.63 2.1.1.63]

Revision as of 11:53, 3 June 2009

  • Description: O6-methylguanine DNA alkyltransferase

Gene name ogt
Synonyms dat
Essential no
Product O6-methylguanine DNA alkyltransferase
Function DNA repair
MW, pI 18 kDa, 7.092
Gene length, protein length 495 bp, 165 aa
Immediate neighbours kinE, mtnS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Ogt context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU13540

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine (according to Swiss-Prot)
  • Protein family: MGMT family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed