Difference between revisions of "DfrA"
| Line 35: | Line 35: | ||
=== Basic information === | === Basic information === | ||
| − | * ''' | + | * '''Locus tag:''' |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
Revision as of 23:49, 2 June 2009
- Description: dihydrofolate reductase
| Gene name | dfrA |
| Synonyms | tmp |
| Essential | yes PubMed |
| Product | dihydrofolate reductase |
| Function | biosynthesis of folate |
| MW, pI | 19 kDa, 5.219 |
| Gene length, protein length | 504 bp, 168 aa |
| Immediate neighbours | ypkP, thyB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH (according to Swiss-Prot)
- Protein family: spmB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure: 1ZDR (Geobacillus stearothermophilus)
- Swiss prot entry: P11045
- KEGG entry: BSU21810
- E.C. number: 1.5.1.3
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
