Difference between revisions of "NupG"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''nupG'' |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| − | * '''Regulation:''' expression activated by glucose (4.3 fold) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | + | * '''Regulation:''' |
| + | ** expression activated by glucose (4.3 fold) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ||
| + | ** repressed by hypoxanthine and guanine, [[PurR]]-independent, [[G-box]][http://www.ncbi.nlm.nih.gov/sites/entrez/12923093 PubMed] | ||
| − | * '''Regulatory mechanism:''' riboswitch [http://www.ncbi.nlm.nih.gov/sites/entrez/12923093 PubMed] | + | * '''Regulatory mechanism:''' [[G-box]]: transcriptional termination/ antitermination [[riboswitch]] [http://www.ncbi.nlm.nih.gov/sites/entrez/12923093 PubMed] |
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 20:14, 31 May 2009
- Description: purine nucleoside transporter
| Gene name | nupG |
| Synonyms | yxjA |
| Essential | no |
| Product | purine nucleoside transporter |
| Function | purine uptake |
| MW, pI | 43 kDa, 7.757 |
| Gene length, protein length | 1191 bp, 397 aa |
| Immediate neighbours | yxjB, yxiT |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: SLC28A transporter family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot), membrane PubMed
Database entries
- Structure:
- Swiss prot entry: P42312
- KEGG entry: BSU39020
- E.C. number:
Additional information
Expression and regulation
- Operon: nupG
- Regulation:
- Regulatory mechanism: G-box: transcriptional termination/ antitermination riboswitch PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
- Hahne et al. (2008) From complementarity to comprehensiveness - targeting the membrane proteome of growing Bacillus subtilis by divergent approaches. Proteomics 8: 4123-4136 PubMed
- Johansen et al. (2003) Definition of a second Bacillus subtilis pur regulon comprising the pur and xpt-pbuX operons plus pbuG, nupG (yxjA), and pbuE (ydhL). J. Bacteriol. 185: 5200-5209. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
