Difference between revisions of "YjbH"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[yjbI]]-[[yjbH]]'' |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 19:19, 28 May 2009
- Description: stimulation of Spx degradation
| Gene name | yjbH |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | stimulation of Spx degradation |
| MW, pI | 31 kDa, 5.206 |
| Gene length, protein length | 825 bp, 275 aa |
| Immediate neighbours | pepF, yjbI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: adaptor protein for ClpXP-catalyzed Spx degradation PubMed
- Protein family: UPF0413 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):contains Zn atoms (coordinated by the N-terminal His-rich region) PubMed
- Effectors of protein activity: Zn atom is released upon treatment with strong oxidants PubMed
- Localization:
Database entries
- Structure:
- Swiss prot entry: O31606
- KEGG entry: BSU11550
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Peter Zuber, Oregon Health and Science University, USA Homepage
Claes von Wachenfeldt, Lund University, Sweden Homepage
Your additional remarks
References
- Garg et al. 2009. The YjbH protein of Bacillus subtilis enhances ClpXP-catalyzed proteolysis of Spx. J. Bacteriol. 191: 1268-1277. PubMed
- Larsson, J. T., A. Rogstam, and C. von Wachenfeldt. 2007. YjbH is a novel negative effector of the disulphide stress regulator, Spx, in Bacillus subtilis. Mol. Microbiol. 66:669-684. PubMed
