Difference between revisions of "GlpD"
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol (according to Swiss-Prot) |
* '''Protein family:''' FAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot) | * '''Protein family:''' FAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot) | ||
Revision as of 15:53, 23 May 2009
- Description: glycerol-3-phosphate dehydrogenase (menaquinone 7)
| Gene name | glpD |
| Synonyms | |
| Essential | no |
| Product | glycerol-3-phosphate dehydrogenase (menaquinone 7) |
| Function | |
| MW, pI | 62 kDa, 8.002 |
| Gene length, protein length | 1665 bp, 555 aa |
| Immediate neighbours | glpK, pgcA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol (according to Swiss-Prot)
- Protein family: FAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): FAD
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P18158
- KEGG entry: BSU09300
- E.C. number: 1.1.5.3
Additional information
Expression and regulation
- Operon: glpD
- Regulation: repressed by glucose (CcpA)
- Regulatory mechanism: CcpA: transcription repression
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Glatz E, Nilsson RP, Rutberg L, Rutberg B (1996) A dual role of the Bacillus subtilis glpD leader and the GlpP protein in the regulated expression of glpD: antitermination and control of mRNA stability. Mol Microbiol 19:319-328. PubMed
- Holmberg C, Rutberg L (1992) An inverted repeat preceding the Bacillus subtilis glpD gene is a conditional terminator of transcription. Mol Microbiol 6:2931-2938. PubMed
- Glatz E, Farewell A, Rutberg B: The Bacillus subtilis glpD leader and antiterminator protein GlpP provide a target for glucose repression in Escherichia coli. FEMS Microbiol Lett 1998;162:93-96. PubMed
- Glatz E, Persson M, Rutberg B: Antiterminator protein GlpP of Bacillus subtilis binds to glpD leader mRNA. Microbiology 1998;144:449-456. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
