Difference between revisions of "PbpB"

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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/Q07868 Q07868]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/Q07868 Q07868]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU15160]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU15160 BSU15160]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''

Revision as of 23:34, 13 May 2009

  • Description: penicillin-binding protein 2B

Gene name pbpB
Synonyms
Essential yes PubMed
Product penicillin-binding protein 2B
Function septation
MW, pI 79 kDa, 9.234
Gene length, protein length 2148 bp, 716 aa
Immediate neighbours ftsL, spoVD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PbpB context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: transpeptidase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot), extracellular (signal peptide) PubMed, localizes to the sporulation septum during sporulation PubMed

Database entries

  • Structure:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: constitutively expressed PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jeff Errington lab
  • Antibody:

Labs working on this gene/protein

Jeff Errington, Newcastle University, UK homepage

Your additional remarks

References

  1. Voigt et al. (2009) Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis. J Mol Microbiol Biotechnol. 16: 53-68 PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed