Difference between revisions of "CymR"
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| − | * '''Description:''' | + | * '''Description:''' pleiotropic regulator of sulphur metabolism <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcription repressor |
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of sulphur metabolism |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 9.879 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 9.879 | ||
Revision as of 15:40, 20 March 2009
- Description: pleiotropic regulator of sulphur metabolism
| Gene name | cymR |
| Synonyms | yrzC |
| Essential | no |
| Product | transcription repressor |
| Function | regulation of sulphur metabolism |
| MW, pI | 11 kDa, 9.879 |
| Gene length, protein length | 333 bp, 111 aa |
| Immediate neighbours | yrvO, yrvN |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: Rrf2 family of transcription regulators
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Effectors of protein activity:
- Interactions: CymR-CysK, the complex is formed in the presence of cysteine, and results in DNA binding and repression of genes of cysteine biosynthesis PubMed
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor: SigA
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Tanous et al. (2008) The CymR regulator in complex with the enzyme CysK controls cysteine metabolism in Bacillus subtilis.J. Biol. Chem. 283: 35551-35560. PubMed
- Even S., Burguiere P., Auger S., Soutourina O., Danchin A., Martin-Verstraete I. (2006) Global control of cysteine metabolism by CymR in Bacillus subtilis. J. Bacteriol 188: 2184-2197 PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
