Difference between revisions of "GlnR"

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(Database entries)
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* '''Description:''' repressor of the ''glnRA'' operon <br/><br/>
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* '''Description:''' transcriptional repressor of the glnRA operon <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional repressor
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|style="background:#ABCDEF;" align="center"| '''Product''' || transcription repressor
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || negative regulation of the glutamine synthetase gene (glnA)
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of glutamine synthesis
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 15 kDa, 9.731   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 15 kDa, 9.731   

Revision as of 16:34, 16 March 2009

  • Description: transcriptional repressor of the glnRA operon

Gene name glnR
Synonyms
Essential no
Product transcription repressor
Function regulation of glutamine synthesis
MW, pI 15 kDa, 9.731
Gene length, protein length 405 bp, 135 aa
Immediate neighbours ynbB, glnA
Gene sequence (+200bp) Protein sequence
Genetic context
GlnR context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): feedback-inhibited GlnA
  • Effectors of protein activity:
  • Interactions: GlnR-GlnA, with feedback-inhibited GlnA, this results in DNA binding
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: expressed in the absence of glutamine PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Susan Fisher, Boston, USA homepage

Your additional remarks

References

  1. Schreier, H. J., Brown, S. W., Hirschi, K. D., Nomellini, J. F. & Sonenshein, A. L. (1989). Regulation of Bacillus subtilis glutamine synthetase gene expression by the product of the glnR gene. J Mol Biol 210, 51-63. PubMed
  2. Brown, S. W., and A. L. Sonenshein. 1996. Autogenous regulation of the Bacillus subtilis glnRA operon. J. Bacteriol. 178: 2450-2454. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed