Difference between revisions of "PbpI"

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* '''Description:''' penicillin-binding protein 4B <br/><br/>
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* '''Description:''' sporulation-specific [[penicillin-binding protein]] 4b <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Product''' || penicillin-binding protein 4B
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[penicillin-binding protein]] 4b
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
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|-
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27310 pbpI]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 65 kDa, 9.012   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 65 kDa, 9.012   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrrS]]'', ''[[greA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrrS]]'', ''[[greA]]''
 
|-
 
|-
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yrrR_nucleotide.txt    Gene sequence     (+200bp)  ]'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27310 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27310 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27310 DNA_with_flanks]
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yrrR_protein.txt Protein sequence]'''
 
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yrrR_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yrrR_context.gif]]
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<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|-
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pbpI_2789686_2791440_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:pbpI_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27310]]
 
|-
 
|-
 
|}
 
|}
  
 
__TOC__
 
__TOC__
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<br/><br/><br/><br/>
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<br/><br/><br/><br/>
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<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
  
 
<br/><br/>
 
<br/><br/>
 +
 +
= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[cell wall synthesis]]}},
 +
{{SubtiWiki category|[[sporulation proteins]]}}
 +
 +
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[SigE regulon]]}},
 +
{{SubtiWiki regulon|[[SigF regulon]]}}
  
 
=The gene=
 
=The gene=
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=== Basic information ===
 
=== Basic information ===
  
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* '''Coordinates:'''
+
* '''Locus tag:''' BSU27310
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27310&redirect=T BSU27310]
  
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* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yrrR.html]
+
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yrrRS.html]
  
 
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13797]
 
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13797]
  
 
=== Additional information===
 
=== Additional information===
 +
 +
  
  
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
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* '''Protein family:'''
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* '''Protein family:''' [[transpeptidase family]] (according to UniProt)
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
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* '''Interactions:'''
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* '''[[SubtInteract|Interactions]]:'''  
 +
** may be part of the [[cell wall biosynthetic complex]] {{PubMed|17981078}}
  
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* '''Localization:'''
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* '''[[Localization]]:'''
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27310&redirect=T BSU27310]
  
 
* '''Structure:'''
 
* '''Structure:'''
  
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* '''Swiss prot entry:'''
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* '''UniProt:''' [http://www.uniprot.org/uniprot/O32032 O32032]
  
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* '''KEGG entry:'''
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27310]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''
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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[pbpI]]-[[yrrS]]'' (according to [http://dbtbs.hgc.jp/COG/prom/yrrRS.html DBTBS])
  
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* '''Operon:'''  
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pbpI_2789686_2791440_-1 pbpI] {{PubMed|22383849}}
  
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* '''Sigma factor:''' [[SigE]] [http://www.ncbi.nlm.nih.gov/sites/entrez/15758244 Link to a summary]
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* '''Sigma factor:''' [[SigE]] {{PubMed|14679248,15758244}}, [[SigF]] {{PubMed|15699190,16497325}}
  
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* '''Regulation:''' expressed during sporulation in the mother cell [http://www.ncbi.nlm.nih.gov/sites/entrez/15758244 Link to a summary]
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* '''Regulation:'''  
 +
** expressed early during sporulation in both cell compartments ([[SigE]] {{PubMed|14679248,15758244}}, [[SigF]] {{PubMed|15699190,16497325}})
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
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* '''Additional information:'''  
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* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
 +
<pubmed>14679248 15699190,16497325 ,15758244  </pubmed>
  
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# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
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[[Category:Protein-coding genes]]

Latest revision as of 09:12, 26 June 2019

Gene name pbpI
Synonyms yrrR
Essential no
Product penicillin-binding protein 4b
Function unknown
Gene expression levels in SubtiExpress: pbpI
MW, pI 65 kDa, 9.012
Gene length, protein length 1752 bp, 584 aa
Immediate neighbours yrrS, greA
Sequences Protein DNA DNA_with_flanks
Genetic context
YrrR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PbpI expression.png
























Categories containing this gene/protein

cell wall synthesis, sporulation proteins

This gene is a member of the following regulons

SigE regulon, SigF regulon

The gene

Basic information

  • Locus tag: BSU27310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

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