Difference between revisions of "Stusti 2018"

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==  What makes RNA such a special molecule – specific chemical and structural features of RNA ==
 
==  What makes RNA such a special molecule – specific chemical and structural features of RNA ==
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== RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair ==
 
== RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair ==
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<pubmed>  24219496 8156586 28979293 26109351</pubmed>
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== Ribozymes (catalytically active RNAs)(Intro)==
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== Ribozymes (catalytically active RNAs) (Intro)==
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== The Ribosome - the role and function of ribosomal RNAs     and the central dogma of molecular biology ==
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== The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology ==
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== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ==
 
== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ==
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<pubmed> 24452469,26682498 25798239 </pubmed>
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== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme & Co ==
 
== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme & Co ==
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<pubmed> 22454536,14730013 10554775 21930585 6297745</pubmed>
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== RNA-based second messengers ==
 
== RNA-based second messengers ==
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== Riboregulation and virulence, targeting by antibiotics ==
 
== Riboregulation and virulence, targeting by antibiotics ==
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== Protein- or tRNA-controlled RNA switches ==
 
== Protein- or tRNA-controlled RNA switches ==
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== RNA thermometers ==
 
== RNA thermometers ==
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== RNA dependent DNA Polymerases - from telomerase to retroviruses==
 
== RNA dependent DNA Polymerases - from telomerase to retroviruses==
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== RNA dependent RNA Polymerases – the RNA replicase ==
 
== RNA dependent RNA Polymerases – the RNA replicase ==
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== CRISPR/Cas: Science – the bacterial “immune” system ==
 
== CRISPR/Cas: Science – the bacterial “immune” system ==
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== CRISPR/Cas: Application and groundbreaking  perspectives ==
 
== CRISPR/Cas: Application and groundbreaking  perspectives ==
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== The mysterious function and role of 6S-RNA and pRNA in bacteria ==
 
== The mysterious function and role of 6S-RNA and pRNA in bacteria ==
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== Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer ==
 
== Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer ==
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<pubmed>   22016848 26186290 21957054 23166520 21930591</pubmed>  
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== Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) ==
 
== Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) ==
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== Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways ==
 
== Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways ==
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Revision as of 12:37, 22 June 2018

Contents

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

What makes RNA such a special molecule – specific chemical and structural features of RNA


RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair


Ribozymes (catalytically active RNAs) (Intro)


The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology


The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity


Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co


RNA-based second messengers

Jan Gundlach, Christina Herzberg, Volkhard Kaever, Katrin Gunka, Tamara Hoffmann, Martin Weiß, Johannes Gibhardt, Andrea Thürmer, Dietrich Hertel, Rolf Daniel, Erhard Bremer, Fabian M Commichau, Jörg Stülke
##Title##
Sci Signal: 2017, 10(475);
[PubMed:28420751] [WorldCat.org] [DOI] (I e)

Christopher P Jones, Adrian R Ferré-D'Amaré
Recognition of the bacterial alarmone ZMP through long-distance association of two RNA subdomains.
Nat Struct Mol Biol: 2015, 22(9);679-85
[PubMed:26280533] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Achim Dickmanns, Jan Gundlach, Ralf Ficner, Jörg Stülke
A jack of all trades: the multiple roles of the unique essential second messenger cyclic di-AMP.
Mol Microbiol: 2015, 97(2);189-204
[PubMed:25869574] [WorldCat.org] [DOI] (I p)

Renée J St-Onge, Henry J Haiser, Mary R Yousef, Emma Sherwood, Natalia Tschowri, Mahmoud Al-Bassam, Marie A Elliot
Nucleotide second messenger-mediated regulation of a muralytic enzyme in Streptomyces.
Mol Microbiol: 2015, 96(4);779-95
[PubMed:25682701] [WorldCat.org] [DOI] (I p)

Gregory S Ducker, Joshua D Rabinowitz
ZMP: a master regulator of one-carbon metabolism.
Mol Cell: 2015, 57(2);203-4
[PubMed:25616065] [WorldCat.org] [DOI] (I p)


Riboregulation and virulence, targeting by antibiotics

Juan J Quereda, Pascale Cossart
Regulating Bacterial Virulence with RNA.
Annu Rev Microbiol: 2017, 71;263-280
[PubMed:28886688] [WorldCat.org] [DOI] (I p)

Petra Dersch, Muna A Khan, Sabrina Mühlen, Boris Görke
Roles of Regulatory RNAs for Antibiotic Resistance in Bacteria and Their Potential Value as Novel Drug Targets.
Front Microbiol: 2017, 8;803
[PubMed:28529506] [WorldCat.org] [DOI] (P e)

Hao Wang, Paul A Mann, Li Xiao, Charles Gill, Andrew M Galgoci, John A Howe, Artjohn Villafania, Christopher M Barbieri, Juliana C Malinverni, Xinwei Sher, Todd Mayhood, Megan D McCurry, Nicholas Murgolo, Amy Flattery, Matthias Mack, Terry Roemer
Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.
Cell Chem Biol: 2017, 24(5);576-588.e6
[PubMed:28434876] [WorldCat.org] [DOI] (I p)

Andreas Matern, Danielle Pedrolli, Stephanie Großhennig, Jörgen Johansson, Matthias Mack
Uptake and Metabolism of Antibiotics Roseoflavin and 8-Demethyl-8-Aminoriboflavin in Riboflavin-Auxotrophic Listeria monocytogenes.
J Bacteriol: 2016, 198(23);3233-3243
[PubMed:27672192] [WorldCat.org] [DOI] (I e)

Aaron M Nuss, Ann Kathrin Heroven, Petra Dersch
RNA Regulators: Formidable Modulators of Yersinia Virulence.
Trends Microbiol: 2017, 25(1);19-34
[PubMed:27651123] [WorldCat.org] [DOI] (I p)

Daniel Dar, Maya Shamir, J R Mellin, Mikael Koutero, Noam Stern-Ginossar, Pascale Cossart, Rotem Sorek
Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria.
Science: 2016, 352(6282);aad9822
[PubMed:27120414] [WorldCat.org] [DOI] (I p)

John A Howe, Hao Wang, Thierry O Fischmann, Carl J Balibar, Li Xiao, Andrew M Galgoci, Juliana C Malinverni, Todd Mayhood, Artjohn Villafania, Ali Nahvi, Nicholas Murgolo, Christopher M Barbieri, Paul A Mann, Donna Carr, Ellen Xia, Paul Zuck, Dan Riley, Ronald E Painter, Scott S Walker, Brad Sherborne, Reynalda de Jesus, Weidong Pan, Michael A Plotkin, Jin Wu, Diane Rindgen, John Cummings, Charles G Garlisi, Rumin Zhang, Payal R Sheth, Charles J Gill, Haifeng Tang, Terry Roemer
Selective small-molecule inhibition of an RNA structural element.
Nature: 2015, 526(7575);672-7
[PubMed:26416753] [WorldCat.org] [DOI] (I p)


Riboswitches


Protein- or tRNA-controlled RNA switches


RNA thermometers


The RNA world and evolution


RNA modification


RNA degradation/processing


Regulation by non-coding RNA



RNA dependent DNA Polymerases - from telomerase to retroviruses


RNA dependent RNA Polymerases – the RNA replicase


CRISPR/Cas: Science – the bacterial “immune” system


CRISPR/Cas: Application and groundbreaking perspectives


The mysterious function and role of 6S-RNA and pRNA in bacteria


Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer


Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)


Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways