tatCD

tatCD
168

component of the TatAD-TatCD twin-arginine translocase

Locus
BSU_02640
Molecular weight
27.96 kDa
Isoelectric point
9.34
Protein length
Gene length
Function
Product
component of the twin-arginine translocation pathway
Essential
no
Synonyms
tatCD, ycbT

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0805 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
286,048  286,776
The protein
Catalyzed reaction/ biological activity
translocation of PhoD PubMed
Protein family
tatC family (with TatCY, according to UniProt)
Structure
4B4A (PDB) (from Aquifex aeolicus, 32% identity) PubMed
Paralogous protein(s)
cell membrane PubMed
Expression and Regulation
Operons
Description
Regulation
expressed under conditions of phosphate limitation (PhoP) PubMed
Regulatory mechanism
PhoP: activation, PubMed, in phoP regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
expression of the operon depends on functional HemAT and CsbC PubMed
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phoDtatCD

2025-07-06 20:44:22

ghost

139

c015e40a74e49c2ee0f16243375748d773825c85

B05615D1A6B638EF19AF5F2CDAAA7BE517BF1E14

Biological materials
Mutant
MGNA-C038 (ycbT::erm), available at the NBRP B. subtilis, Japan
BKE02640 (tatCD::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTCAAAAAAGCCCTCCCT,  downstream forward: _UP4_AGGGAAGAAACAGCGGCGGC
BKK02640 (tatCD::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTCAAAAAAGCCCTCCCT,  downstream forward: _UP4_AGGGAAGAAACAGCGGCGGC
Labs working on this gene/protein
Jan Maarten van Dijl, University of Groningen, The Netherlands, Homepage
References
Reviews
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Original Publications
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A58C9B9BB6574662A44AF0C7A94DFFE368B740E2

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Time of last update: 2025-07-14 02:53:07

Author of last update: Jstuelk