qcrA

qcrA
168

Rieske factor, menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit), component of the cytochrome bc1 complex

Locus
BSU_22560
Molecular weight
18.59 kDa
Isoelectric point
6.08
Protein length
Gene length
Function
respiration
Product
menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit)
Essential
no
Synonyms
qcrA, bfcA, petC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0723 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,364,589 → 2,365,092
Phenotypes of a mutant
severe growth defect PubMed
The protein
Rieske domain (aa 59-158) (according to UniProt)
Fe-S cluster PubMed
Structure
2ZT9 (PDB) (from Nostoc sp., 31% identity) PubMed
cell membrane PubMed
delivered to the membrane by the TatAY-TatCY protein secretion system, this depends on prior dusulfide bond formation and co-factor insertion PubMed
Expression and Regulation
Operons
Description
Regulation
induced by oxygen limitation (ResD) PubMed
Regulatory mechanism
ResD: activation, PubMed, in resD regulon
CcpA: repression, PubMed, in ccpA regulon
AbrB: repression, PubMed, in abrB regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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qcrAqcrC

2025-02-15 16:03:52

ghost

85

7d8c3c6cc2ec23530c055f733cdbc2588ec9af8d

4BEBC1EEDB0388339F5862B8B44D227B69748126

Additional information
highly expressed at high iron concentrations PubMed
Biological materials
Mutant
BKE22560 (ΔqcrA::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATCTCTTCTCCCCCCTCTA,  downstream forward: _UP4_GCAAAGCCTAAGGGGGAAGG
BKK22560 (ΔqcrA::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATCTCTTCTCCCCCCTCTA,  downstream forward: _UP4_GCAAAGCCTAAGGGGGAAGG
References
Reviews
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Original Publications
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Time of last update: 2025-05-01 14:49:06

Author of last update: Jstuelk