nasD
168
assimilatory nitrite reductase (subunit)
Locus
BSU_03300
Molecular weight
88.24 kDa
Isoelectric point
4.95
Function
utilization of nitrite as nitrogen source
Product
assimilatory nitrite reductase (subunit)
Essential
no
E.C.
1.7.1.4
Synonyms
nasD, nasBC, nirB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1251 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
355,764 → 358,181
The protein
Catalyzed reaction/ biological activity
2 H2O + 3 NADP+ + NH4+ --> 5 H+ + 3 NADPH + nitrite (according to UniProt)
2 H2O + 3 NAD+ + NH4+ --> 5 H+ + 3 NADH + nitrite (according to UniProt)
Protein family
nitrite and sulfite reductase 4Fe-4S domain family (with CysI, according to UniProt)
Structure
3KLJ (PDB) (from Clostridium acetobutylicum, corresponds to aa 5 ... 399, 32% identity) PubMed
Paralogous protein(s)
Expression and Regulation
Operons
Biological materials
Mutant
References
Reviews
Bacterial nitrate assimilation: gene distribution and regulation.
Biochemical Society transactions. 2011 Dec; 39(6):1838-43. doi:10.1042/BST20110688. PMID:22103536
Functional, biochemical and genetic diversity of prokaryotic nitrate reductases.
Cellular and molecular life sciences : CMLS. 2001 Feb; 58(2):165-78. . PMID:11289299
Original Publications
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Time of last update: 2025-06-12 01:42:20
Author of last update: Jstuelk