rplL

168

ribosomal protein bL12

Locus: BSU_01050

Molecular weight: 12.61 kDa

Isoelectric point: 4.36

Protein length: 123 aa

Gene length: 372 bp

Function: translation

Product: ribosomal protein L12 (bL12)

Essential: yes

Synonyms: rplL

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0222 (Galperin et al., 2021)

Gene

Coordinates: 120,607 120,978

Phenotypes of a mutant

• essential PubMed

The protein

Protein family

• Bacterial ribosomal protein bL12 family (single member, according to UniProt)

Structure

• 3J9W (PDB) (the ribosome) PubMed
• P02394 (AlphaFold)

Localization

• ribosome (according to UniProt)

Additional information

• belongs to the 100 most abundant proteins PubMed

Expression and Regulation

Operons

• Genes: rplJ-rplL

  Description: PubMed

  Regulation

  • termination/ antitermination (L10-L12₄ complex) PubMed

  Regulatory mechanism

  • RplJ: termination, at excess of the RplJ-RplL₄ complex, in rplJ regulon
  • stringent response: negative regulation, in stringent response
  • RplL: termination, at excess of the RplJ-RplL₄ complex, in rplL regulon

• Genes: rplK-rplA-BSU_misc_RNA_3-rplJ-rplL

  Description: PubMed

  Regulation

  • Rel dependent downregulation (Class I) during stringent response PubMed

  Regulatory mechanism

  • stringent response: negative regulation, PubMed, in stringent response

References

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