Difference between revisions of "Elongasome"
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<big>'''A protein complex that catalyzes peptidoglycan biosynthesis and is thereby involved in maintaining [[cell shape]]'''</big> | <big>'''A protein complex that catalyzes peptidoglycan biosynthesis and is thereby involved in maintaining [[cell shape]]'''</big> | ||
+ | ==Complex members== | ||
+ | * cell wall biosynthetic enzymes at the outer side of the membrane: [[penicillin-binding proteins]] ([[PbpA]], [[PbpH]], perhaps also [[PbpC]], [[DacC]], [[PbpI]]) | ||
+ | * transmembrane proteins: [[MreC]], [[MreD]], [[RodA]], [[RodZ]], they couple the cytosolic actin-like proteins to the extracellular peptidoglycan-synthesizing machinery | ||
+ | * actin-like proteins at the inner surface of the membrane: [[MreB]], [[MreBH]], [[Mbl]], the polymers control/restrict the mobility of the cell wall elongation enzyme complex | ||
==Related pages== | ==Related pages== | ||
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* [[cell wall synthesis]] | * [[cell wall synthesis]] | ||
* [http://subtiwiki.uni-goettingen.de/pathways/cellwall.html Cell wall synthesis in SubtiPathways] | * [http://subtiwiki.uni-goettingen.de/pathways/cellwall.html Cell wall synthesis in SubtiPathways] | ||
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+ | ==Labs working on the complex== | ||
+ | * [[Rut Carballido-Lopez]], Jouy-en-Josas | ||
+ | * [[Jeff Errington]], Newcastle upon Tyne | ||
+ | * [[David Rudner]], New York | ||
==Important publications== | ==Important publications== | ||
− | + | <pubmed>21636744 21636745 23848140 21725336 24094808 26029191</pubmed> | |
− | + | ||
− | + | ==Back to [[SubtInteract]]== | |
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Latest revision as of 15:33, 7 July 2015
A protein complex that catalyzes peptidoglycan biosynthesis and is thereby involved in maintaining cell shape
Contents
Complex members
- cell wall biosynthetic enzymes at the outer side of the membrane: penicillin-binding proteins (PbpA, PbpH, perhaps also PbpC, DacC, PbpI)
- transmembrane proteins: MreC, MreD, RodA, RodZ, they couple the cytosolic actin-like proteins to the extracellular peptidoglycan-synthesizing machinery
- actin-like proteins at the inner surface of the membrane: MreB, MreBH, Mbl, the polymers control/restrict the mobility of the cell wall elongation enzyme complex
Related pages
Labs working on the complex
- Rut Carballido-Lopez, Jouy-en-Josas
- Jeff Errington, Newcastle upon Tyne
- David Rudner, New York
Important publications