rsbX

rsbX
168

protein serine phosphatase, feedback PP2C, dephosphorylates RsbS and RsbR

Locus
BSU_04740
Molecular weight
22.00 kDa
Isoelectric point
6.23
Protein length
Gene length
Function
control of SigB activity
Product
protein serine phosphatase, feedback PP2C
Essential
no
E.C.
3.1.3.3
Synonyms
rsbX

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2208 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
523,650  524,249
The protein
Catalyzed reaction/ biological activity
dephosphorylation of RsbR-P PubMed and RsbS-S59-P PubMed
H2O + O-phospho-L-(or D)serine --> L-(or D)serine + phosphate (according to UniProt)
PPM-type phosphatase domain (aa 11-198) (according to UniProt)
Structure
Expression and Regulation
Operons
Description
Regulation
''rsbV:'' induced by stress (SigB) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigB: sigma factor, PubMed, in sigB regulon
Open in new tab

rsbRrsbX

2024-12-19 03:54:02

ghost

188

5f220975cc2493224a8aa0770ee2187c815a2127

3EFC8DC1AC54632D4F2AC30497749AB5CCA3A39F

Description
Regulation
''rsbV:'' induced by stress (SigB) PubMed
Open in new tab

rsbVrsbX

2024-12-06 12:20:01

ghost

115

c245857c04f8cca86e1f0627f3b25353c582e66e

E6CC0B507AA5819A4C5EBF800596629708A2B80D

Biological materials
Mutant
BKE04740 (rsbX::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CTCGTTTTCTTCAACCTGGA,  downstream forward: _UP4_TAAAAAACCAGAAAAAGAAG
BKK04740 (rsbX::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CTCGTTTTCTTCAACCTGGA,  downstream forward: _UP4_TAAAAAACCAGAAAAAGAAG
Labs working on this gene/protein
Bill Haldenwang, San Antonio, USA
Chet Price, Davis, USA homepage
References
Reviews
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Original Publications
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8536803BDFB58D43C52961931F609933E49E989D

Page visits: 4729

Time of last update: 2024-12-20 01:24:23

Author of last update: Jstuelk