Difference between revisions of "ConE"
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| + | * '''Description:''' required for conjugation of ICE''Bs1'', part of the type IV secretion system for DNA transfer <br/><br/> | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || part of the type IV secretion system for DNA transfer |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || conjugative transfer of ICEBs1 | |style="background:#ABCDEF;" align="center"|'''Function''' || conjugative transfer of ICEBs1 | ||
Revision as of 16:05, 28 May 2015
- Description: required for conjugation of ICEBs1, part of the type IV secretion system for DNA transfer
| Gene name | conE |
| Synonyms | yddE |
| Essential | no |
| Product | part of the type IV secretion system for DNA transfer |
| Function | conjugative transfer of ICEBs1 |
| Gene expression levels in SubtiExpress: conE | |
| MW, pI | 96 kDa, 5.511 |
| Gene length, protein length | 2493 bp, 831 aa |
| Immediate neighbours | yddD, yddF |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04940
Phenotypes of a mutant
Defective for conjugal transfer of ICEBs1
Database entries
- BsubCyc: BSU04940
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: required for conjugative transfer of ICEBs1, putative ATPase PubMed
- Protein family: HerA/FtsK Superfamily of ATPases including the well-studied proteins FtsK, SpoIIIE, VirB4, and VirD4
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization:
- Located at the cell poles, in close association with the membrane
Database entries
- BsubCyc: BSU04940
- Structure:
- UniProt: P96642
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Melanie Barker Berkmen, Suffolk University, Boston, MA Homepage
Your additional remarks
References
Melanie B Berkmen, Catherine A Lee, Emma-Kate Loveday, Alan D Grossman
Polar positioning of a conjugation protein from the integrative and conjugative element ICEBs1 of Bacillus subtilis.
J Bacteriol: 2010, 192(1);38-45
[PubMed:19734305]
[WorldCat.org]
[DOI]
(I p)
