acoB
168
acetoin dehydrogenase E1 component (TPP-dependent beta subunit)
Locus
BSU_08070
Molecular weight
36.69 kDa
Isoelectric point
4.4
Function
acetoin utilization
Product
acetoin dehydrogenase E1 component (TPP-dependent beta subunit)
Essential
no
Synonyms
acoB, yfjJ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0022 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
880,007 881,035
Phenotypes of a mutant
defective in the the ability to support the growth of Synechococcus leopoliensis CCAP1405/1 on agar media PubMed
The protein
Structure
3DUF (PDB) (PDH from Geobacillus stearothermophilus, 43% identity) PubMed
Paralogous protein(s)
Membrane-proximal (Spotty) PubMed
Expression and Regulation
Operons
Description
Regulation
Regulatory mechanism
AcoR: activation, (interaction with SigL-containing RNA polymerase) [ PubMed|11274109], in acoR regulon
Fnr: indirect positive regulation, in fnr regulon
Sigma factors
Additional information
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Additional information
the mRNA is very stable (> 15 min) PubMed
Biological materials
Mutant
MGNA-C281 (acoB::erm), available at the NBRP B. subtilis, Japan
Two-hybrid system
B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jörg Stülke's lab
Labs working on this gene/protein
Michel Debarbouille, Pasteur Institute, Paris, France Homepage
References
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Time of last update: 2024-12-18 15:50:30
Author of last update: LKrueger