gerPA

168

spore germination protein, facilitates access of nutrient germinants to their cognate germinant receptors in spores’ inner membrane

Locus: BSU_10720

Molecular weight: 7.41 kDa

Isoelectric point: 4.46

Protein length: 73 aa

Gene length: 222 bp

Function: germination

Product: unknown

Essential: no

E.C.: null

Synonyms: gerPA, yisH

Genomic Context

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Categories containing this gene/protein

Lifestyles, Sporulation, Germination, Additional germination proteins

List of homologs in different organisms, belongs to COG5906 (Galperin et al., 2021)

This gene is a member of the following regulons

GerE regulon, SigK regulon

Gene

Coordinates: 1,150,206 → 1,150,427

The protein

Protein family

GerPA/GerPF family (according to UniProt)

Structure

O06721 (AlphaFold)

Expression and Regulation

Operons

Genes: gerPA-gerPB-gerPC-gerPD-gerPE-gerPF

Description: PubMed

Regulation

expressed during sporulation in the mother cell (SigK) PubMed

Regulatory mechanism

GerE: repression, in gerE regulon

Sigma factors

SigK: sigma factor, PubMed, in sigK regulon

Additional information

A ncRNA is predicted between 'gerPA' and 'yisI' PubMed

Biological materials

Mutant

BKE10720 (ΔgerPA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACGAGCACATCCTTTGT,  downstream forward: _UP4_AATGCGTAAAAGGAGTGAGG
BKK10720 (ΔgerPA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACGAGCACATCCTTTGT,  downstream forward: _UP4_AATGCGTAAAAGGAGTGAGG

References

Reviews

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Original Publications

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