fliI

fliI
168

flagellar-specific ATPase for the export of flagellar proteins

Locus
BSU_16240
Molecular weight
47.71 kDa
Isoelectric point
5.6
Protein length
Gene length
Function
export of flagellar proteins
Product
flagellar-specific ATPase
Essential
no
E.C.
3.6.3.14
Synonyms
fliI

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1157 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,695,877  1,697,193
Phenotypes of a mutant
loss of motility PubMed
a mutant has been selected during growth at low pressure PubMed
inactivation of ''fliI'' confers resistance to high concentrations of Zn(II) PubMed
defective in Swarming motility PubMed
The protein
Catalyzed reaction/ biological activity
ATP + 4 H+ + H2O --> ADP + 5 H+ + phosphate (according to UniProt)
Protein family
ATPase alpha/beta chains family (with AtpA and AtpD, according to UniProt)
Structure
2DPY (PDB) (from Salmonella enterica, 50% identity) PubMed
cytoplasm, as part of the flagellum attached to the membrane PubMed
Expression and Regulation
Operons
Description
Regulation
expression during spore germination is strongly reduced under conditions of osmotic stress PubMed
Regulatory mechanism
Spo0A: repression, in spo0A regulon
SwrA: activation, in swrA regulon
CodY: repression, in codY regulon
DegU: repression, in degU regulon
SinR: transcription elongation, binding of the SinR-SlrR heteromer to sites within fliE and fliI results in inhibition of transcription elongation PubMed, in sinR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigD: sigma factor, PubMed, in sigD regulon
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flgBswrB

2025-04-30 03:08:43

Jstuelk

175

024d59ae468aa14568753f57122b789c39ed6c06

4D920B925DA071AE7390E022B9AB625E40B7B2AC

Biological materials
Mutant
BKE16240 (fliI::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_ACAATCTATCAGACTCTGTG,  downstream forward: _UP4_TTGACAGGAAATGAGGAATA
BKK16240 (fliI::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_ACAATCTATCAGACTCTGTG,  downstream forward: _UP4_TTGACAGGAAATGAGGAATA
References
Reviews
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Original Publications
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Time of last update: 2025-04-29 23:19:47

Author of last update: Jstuelk