yciB

168

putative L,D-transpeptidase

Locus: BSU_03350

Molecular weight: 21.94 kDa

Isoelectric point: 6.18

Protein length: 194 aa

Gene length: 585 bp

Function: unknown

Product: putative L,D-transpeptidase

Essential: no

Synonyms: yciB

Genomic Context

Hide small RNAsZoom:

Categories containing this gene/protein

Cellular processes, Cell envelope and cell division, Cell wall synthesis, Biosynthesis of peptidoglycan

Metabolism, Additional metabolic pathways, Biosynthesis of cell wall components, Biosynthesis of peptidoglycan

Groups of genes, Membrane proteins

List of homologs in different organisms, belongs to COG1376 (Galperin et al., 2021)

This gene is a member of the following regulons

SigA regulon, Zur regulon

Gene

Coordinates: 365,170  365,754

The protein

Protein family

YkuD family (with Ldt and YqjB, according to UniProt)

Structure

4LZH (PDB) (from Klebsiella pneumoniae, 27% identity)
C0SP99 (AlphaFold)

Localization

lipoprotein, cell membrane at the cell poles PubMed

Expression and Regulation

Operons

Genes: folEB-yciB-yczL-zagA

Description: PubMed

Regulation

folE2: induced by zinc starvation (Zur) PubMed

Regulatory mechanism

Zur: repression, in the presence of zinc PubMed, in zur regulon

Sigma factors

SigA: sigma factor, PubMed, in sigA regulon

Biological materials

Mutant

MGNA-B998 (yciB::erm), available at the NBRP B. subtilis, Japan
BKE03350 (yciB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGCAATAATGAATAATGAGA,  downstream forward: _UP4_TGAATTGAAAACCGTTGACA
BKK03350 (yciB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGCAATAATGAATAATGAGA,  downstream forward: _UP4_TGAATTGAAAACCGTTGACA

References

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