Difference between revisions of "SsrA"

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(Original publications)
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* '''Additional information:'''
 
* '''Additional information:'''
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** maturation of tmRNA on the 3' and 5' ends depends on [[rnz|RNase Z]] and rnpB, respectively {{PubMed|25402410}}
  
 
=Biological materials =
 
=Biological materials =
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==Reviews==
 
==Reviews==
 
<pubmed> 12730326 23479438,19609260</pubmed>
 
<pubmed> 12730326 23479438,19609260</pubmed>
 
 
==Original publications==
 
==Original publications==
<pubmed>18977770,11395451,17369301,15805528,10881189,14766921, 22211522</pubmed>
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<pubmed>18977770,11395451,17369301,15805528,10881189,14766921, 22211522 25402410 </pubmed>
  
 
[[Category:small RNA]]
 
[[Category:small RNA]]

Revision as of 12:18, 18 November 2014

  • Description: tmRNA

Gene name ssrA
Synonyms
Essential no
Product tmRNA
Function trans-translation
Gene length bp
Immediate neighbours yvaG, smpB
Gene sequence (+200bp)
Genetic context
SsrA context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

translation, ncRNA

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

  • impaired growth at high and low temperatures PubMed
  • inactivation of ssrA restores beta-lactam resistance in a sigM mutant PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]
  • Structure:

Additional information

Expression and regulation

  • Additional information:
    • maturation of tmRNA on the 3' and 5' ends depends on RNase Z and rnpB, respectively PubMed

Biological materials

  • Mutant: GP323 (cat), available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/RNA

Your additional remarks

References

Reviews

Noël Molière, Kürşad Turgay
General and regulatory proteolysis in Bacillus subtilis.
Subcell Biochem: 2013, 66;73-103
[PubMed:23479438] [WorldCat.org] [DOI] (P p)

Janine Kirstein, Noël Molière, David A Dougan, Kürşad Turgay
Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+ proteases.
Nat Rev Microbiol: 2009, 7(8);589-99
[PubMed:19609260] [WorldCat.org] [DOI] (I p)

Jeffrey H Withey, David I Friedman
A salvage pathway for protein structures: tmRNA and trans-translation.
Annu Rev Microbiol: 2003, 57;101-23
[PubMed:12730326] [WorldCat.org] [DOI] (P p)

Original publications