Difference between revisions of "FlhA"

From SubtiWiki
Jump to: navigation, search
Line 1: Line 1:
* '''Description:''' flagella-associated protein <br/><br/>
+
* '''Description:''' part of the flagellar type III export apparatus <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 10: Line 10:
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || flagella-associated protein
+
|style="background:#ABCDEF;" align="center"| '''Product''' || part of the flagellar type III export apparatus
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || movement and chemotaxis
+
|style="background:#ABCDEF;" align="center"|'''Function''' || export of flagellum components
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16390 flhA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16390 flhA]
Line 43: Line 43:
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
 
{{SubtiWiki category|[[motility and chemotaxis]]}},
 
{{SubtiWiki category|[[motility and chemotaxis]]}},
 +
{{SubtiWiki category|[[protein secretion]]}},
 
{{SubtiWiki category|[[membrane proteins]]}}
 
{{SubtiWiki category|[[membrane proteins]]}}
  
Line 57: Line 58:
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* no secretion of [[FlgM]], permanent inhibition of [[SigD]] {{PubMed|25313396}}
  
 
=== Database entries ===
 
=== Database entries ===
Line 66: Line 68:
  
 
=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
Line 157: Line 156:
 
=References=
 
=References=
  
<pubmed>8097015, 20534509,14651647,9657996,8157612,15175317 17850253</pubmed>
+
<pubmed>8097015, 20534509,14651647,9657996,8157612,15175317 17850253 25313396</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:14, 27 October 2014

  • Description: part of the flagellar type III export apparatus

Gene name flhA
Synonyms
Essential no
Product part of the flagellar type III export apparatus
Function export of flagellum components
Gene expression levels in SubtiExpress: flhA
Interactions involving this protein in SubtInteract: FlhA
MW, pI 73 kDa, 4.637
Gene length, protein length 2031 bp, 677 aa
Immediate neighbours flhB, flhF
Sequences Protein DNA DNA_with_flanks
Genetic context
FlhA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FlhA expression.png















Categories containing this gene/protein

motility and chemotaxis, protein secretion, membrane proteins

This gene is a member of the following regulons

CodY regulon, SigD regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU16390

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: FHIPEP (flagella/HR/invasion proteins export pore) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 167 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References