RemA

• Description: transcriptional regulator of the extracellular matrix genes, acts in parallel to SinR, AbrB, and DegU
  
  

Gene name	remA
Synonyms	ylzA
Essential	no
Product	regulator of the extracellular matrix genes
Function	control of biofilm formation
Gene expression levels in SubtiExpress: remA
Metabolic function and regulation of this protein in SubtiPathways: remA
MW, pI	9 kDa, 7.178
Gene length, protein length	267 bp, 89 aa
Immediate neighbours	yloC, gmk
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, biofilm formation, sporulation proteins

This gene is a member of the following regulons

SigF regulon

The gene

Basic information

• Locus tag: BSU15670

Database entries

• BsubCyc: BSU15670

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • binds opuAA, tapA, and epsA promoter regions (upstream of the actual promoter) to activate transcription PubMed
  • binds DNA with high co-operativity due to low conserrvation of binding sites PubMed

• Protein family: UPF0296 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU15670

• Structure:

• UniProt: Q7WY72

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: remA PubMed

• Sigma factor: SigF PubMed

• Regulation:
  • expressed during vegetative growth and early during sporulation in the forespore (SigF) PubMed
• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 280 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Daniel Kearns, Indiana University, Bloomington, USA, homepage