yfmP

168

transcription repressor (MerR family) of the yfmP-yfmO operon

Locus: BSU_07390

Molecular weight: 16.36 kDa

Isoelectric point: 5.23

Protein length: 140 aa

Gene length: 423 bp

Function: regulation of the yfmP-yfmO operon

Product: transcription repressor (MerR family)

Essential: no

Synonyms: yfmP

Genomic Context

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List of homologs in different organisms, belongs to COG0789 (Galperin et al., 2021)

Gene

Coordinates: 812,140  812,562

The protein

Protein family

• MerR family

Domains

• HTH merR-type domain (aa 1-73) (according to UniProt)

Structure

• 3QAO (PDB) (from Listeria monocytogenes, 29% identity)
• O06474 (AlphaFold)

Expression and Regulation

Operons

• Genes: yfmP-yfmO

  Description: PubMed

  Regulatory mechanism

  • YfmP: repression, PubMed, in yfmP regulon

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon

Biological materials

Mutant

• MGNA-C236 (yfmP::erm), available at the NBRP B. subtilis, Japan
• BKE07390 (yfmP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGGTAAATCCCCCTTCGC,  downstream forward: _UP4_TGAAAAGTTTGTTAAACGCT
• BKK07390 (yfmP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGGTAAATCCCCCTTCGC,  downstream forward: _UP4_TGAAAAGTTTGTTAAACGCT

References

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